Cargando…

Involvement of Beclin-1 in axonal protection by short-term hyperglycemia against TNF-induced optic nerve damage

Beclin-1 serves a pivotal role in autophagosome formation. A previous study demonstrated that streptozotocin-induced hyperglycemia (HG) ameliorates axonal loss induced by tumor necrosis factor (TNF) with upregulation of autophagy in rats. The aim of present study was to examine whether Beclin-1 is i...

Descripción completa

Detalles Bibliográficos
Autores principales: Sase, Kana, Kitaoka, Yasushi, Tsukahara, Chihiro, Takagi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236285/
https://www.ncbi.nlm.nih.gov/pubmed/30365082
http://dx.doi.org/10.3892/mmr.2018.9568