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MrgX2-mediated internalization of LL-37 and degranulation of human LAD2 mast cells

LL-37 is the sole antimicrobial peptide of human cathelicidin comprising 37 amino acids, which is expressed mainly in epithelial cells and neutrophils, and activates mast cells. In the present study, in order to elucidate the mechanism of mast cell activation by LL-37, the associations between the i...

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Detalles Bibliográficos
Autores principales: Murakami, Taisuke, Suzuki, Kaori, Niyonsaba, Francois, Tada, Hiroyuki, Reich, Johannes, Tamura, Hiroshi, Nagaoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236315/
https://www.ncbi.nlm.nih.gov/pubmed/30280189
http://dx.doi.org/10.3892/mmr.2018.9532