One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate

1-substituted-3-(2-phenylquinazolin-4-yl) thioureas (7) were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenyl- imino)phenylmethyl] thioureas (3). These compounds in turn were prepared by the reaction of N-(2-cyanophenyl)benzimidoyl isothiocyanate (2) with primar...

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Autores principales: Fathalla, W., Čajan, M., Marek, J., Pazdera, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236346/
http://dx.doi.org/10.3390/60700588
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author Fathalla, W.
Čajan, M.
Marek, J.
Pazdera, P.
author_facet Fathalla, W.
Čajan, M.
Marek, J.
Pazdera, P.
author_sort Fathalla, W.
collection PubMed
description 1-substituted-3-(2-phenylquinazolin-4-yl) thioureas (7) were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenyl- imino)phenylmethyl] thioureas (3). These compounds in turn were prepared by the reaction of N-(2-cyanophenyl)benzimidoyl isothiocyanate (2) with primary amines. The structures of products 7 were confirmed by FTIR, (1)H-NMR, (13)C-NMR, mass spectroscopy and X-ray crystallography.
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spelling pubmed-62363462018-11-20 One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate Fathalla, W. Čajan, M. Marek, J. Pazdera, P. Molecules Article 1-substituted-3-(2-phenylquinazolin-4-yl) thioureas (7) were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenyl- imino)phenylmethyl] thioureas (3). These compounds in turn were prepared by the reaction of N-(2-cyanophenyl)benzimidoyl isothiocyanate (2) with primary amines. The structures of products 7 were confirmed by FTIR, (1)H-NMR, (13)C-NMR, mass spectroscopy and X-ray crystallography. MDPI 2001-06-30 /pmc/articles/PMC6236346/ http://dx.doi.org/10.3390/60700588 Text en © 2001 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Fathalla, W.
Čajan, M.
Marek, J.
Pazdera, P.
One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title_full One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title_fullStr One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title_full_unstemmed One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title_short One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyano- phenyl)benzimidoyl isothiocyanate
title_sort one-pot quinazolin-4-yl-thiourea synthesis via n-(2-cyano- phenyl)benzimidoyl isothiocyanate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236346/
http://dx.doi.org/10.3390/60700588
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AT marekj onepotquinazolin4ylthioureasynthesisvian2cyanophenylbenzimidoylisothiocyanate
AT pazderap onepotquinazolin4ylthioureasynthesisvian2cyanophenylbenzimidoylisothiocyanate

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