One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate

1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, (1)H-NMR, (13)C-NMR, mass spec...

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Autores principales: Fathalla., Walid M., Čajan, Michal, Marek, Jaromír, Pazdera,  Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236347/
http://dx.doi.org/10.3390/60700574
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author Fathalla., Walid M.
Čajan, Michal
Marek, Jaromír
Pazdera,  Pavel
author_facet Fathalla., Walid M.
Čajan, Michal
Marek, Jaromír
Pazdera,  Pavel
author_sort Fathalla., Walid M.
collection PubMed
description 1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, (1)H-NMR, (13)C-NMR, mass spectroscopy and X-ray crystallography.
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spelling pubmed-62363472018-11-20 One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate Fathalla., Walid M. Čajan, Michal Marek, Jaromír Pazdera,  Pavel Molecules Article 1,1-Disubstituted-3-(2-phenyl-3H-quinazolin-4-ylidene)thioureas (8) were synthesized in a one pot reaction of N-(2-cyanophenyl)benzimidoyl isothicyanate (3) with secondary amines. The products underwent transamination reactions. Compounds 8a-8g were identified by FTIR, (1)H-NMR, (13)C-NMR, mass spectroscopy and X-ray crystallography. MDPI 2001-06-30 /pmc/articles/PMC6236347/ http://dx.doi.org/10.3390/60700574 Text en © 2001 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Fathalla., Walid M.
Čajan, Michal
Marek, Jaromír
Pazdera,  Pavel
One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title_full One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title_fullStr One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title_full_unstemmed One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title_short One-Pot Quinazolin-4-ylidenethiourea Synthesis via N-(2-Cyanophenyl)benzimidoyl isothiocyanate
title_sort one-pot quinazolin-4-ylidenethiourea synthesis via n-(2-cyanophenyl)benzimidoyl isothiocyanate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236347/
http://dx.doi.org/10.3390/60700574
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