Synthesis of Camalexin

- In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl L-cysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analy...

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Detalles Bibliográficos
Autores principales: Dzurilla, M., Kutschy, P., Zaletova, J., Ruzinsky, M., Kovacik, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236355/
http://dx.doi.org/10.3390/60900716
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author Dzurilla, M.
Kutschy, P.
Zaletova, J.
Ruzinsky, M.
Kovacik, V.
author_facet Dzurilla, M.
Kutschy, P.
Zaletova, J.
Ruzinsky, M.
Kovacik, V.
author_sort Dzurilla, M.
collection PubMed
description - In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl L-cysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, (1)H NMR, (13)C NMR and mass spectroscopy.
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spelling pubmed-62363552018-11-19 Synthesis of Camalexin Dzurilla, M. Kutschy, P. Zaletova, J. Ruzinsky, M. Kovacik, V. Molecules Article - In this paper we describe a new method for the synthesis of camalexin (1) based on the reaction of 1-(tert-butoxycarbonyl)indole-3-carboxaldehyde with methyl L-cysteinate hydrochloride, followed by oxidation and decarboxylation. Compounds 1, and intermediates 5-7 were identified by elemental analysis, (1)H NMR, (13)C NMR and mass spectroscopy. MDPI 2001-08-31 /pmc/articles/PMC6236355/ http://dx.doi.org/10.3390/60900716 Text en © 2001 by MDPI (http://www.mdpi.org). Reproduction is permitted for non-commercial purposes
spellingShingle Article
Dzurilla, M.
Kutschy, P.
Zaletova, J.
Ruzinsky, M.
Kovacik, V.
Synthesis of Camalexin
title Synthesis of Camalexin
title_full Synthesis of Camalexin
title_fullStr Synthesis of Camalexin
title_full_unstemmed Synthesis of Camalexin
title_short Synthesis of Camalexin
title_sort synthesis of camalexin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236355/
http://dx.doi.org/10.3390/60900716
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AT kutschyp synthesisofcamalexin
AT zaletovaj synthesisofcamalexin
AT ruzinskym synthesisofcamalexin
AT kovacikv synthesisofcamalexin

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