Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride

Both pyrophosphoryl chloride and phosphorus oxychloride react with aryl aliphatic acids to form mixed anhydrides which undergo intramolecular acylation to afford cyclic ketones without the addition of a Friedel-Crafts catalyst. Aryl and aroyl-benzoic acids could be cyclized to the corresponding anth...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Sayrafi, Sami, Rayyan, Saleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236387/
http://dx.doi.org/10.3390/60300279
_version_ 1783371024943808512
author El-Sayrafi, Sami
Rayyan, Saleh
author_facet El-Sayrafi, Sami
Rayyan, Saleh
author_sort El-Sayrafi, Sami
collection PubMed
description Both pyrophosphoryl chloride and phosphorus oxychloride react with aryl aliphatic acids to form mixed anhydrides which undergo intramolecular acylation to afford cyclic ketones without the addition of a Friedel-Crafts catalyst. Aryl and aroyl-benzoic acids could be cyclized to the corresponding anthrones and anthraquinones respectively.
format Online
Article
Text
id pubmed-6236387
institution National Center for Biotechnology Information
language English
publishDate 2001
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62363872018-11-19 Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride El-Sayrafi, Sami Rayyan, Saleh Molecules Article Both pyrophosphoryl chloride and phosphorus oxychloride react with aryl aliphatic acids to form mixed anhydrides which undergo intramolecular acylation to afford cyclic ketones without the addition of a Friedel-Crafts catalyst. Aryl and aroyl-benzoic acids could be cyclized to the corresponding anthrones and anthraquinones respectively. MDPI 2001-03-31 /pmc/articles/PMC6236387/ http://dx.doi.org/10.3390/60300279 Text en © 2001 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes
spellingShingle Article
El-Sayrafi, Sami
Rayyan, Saleh
Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title_full Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title_fullStr Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title_full_unstemmed Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title_short Intramolecular Acylation of Aryl- and Aroyl-Aliphatic Acids by the Action of Pyrophosphoryl Chloride and Phosphorus Oxychloride
title_sort intramolecular acylation of aryl- and aroyl-aliphatic acids by the action of pyrophosphoryl chloride and phosphorus oxychloride
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236387/
http://dx.doi.org/10.3390/60300279
work_keys_str_mv AT elsayrafisami intramolecularacylationofarylandaroylaliphaticacidsbytheactionofpyrophosphorylchlorideandphosphorusoxychloride
AT rayyansaleh intramolecularacylationofarylandaroylaliphaticacidsbytheactionofpyrophosphorylchlorideandphosphorusoxychloride

Ejemplares similares