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Synthesis of Acridine-based DNA Bis-intercalating Agents
Methods for the synthesis of N(1), N(8)-bis(9-acridinyl)-N(4)-(4-hydroxybenzyl)-spermidine and N(1), N(7)-(hydroxybenzyl)-bis-(3-aminopropyl)amine were investigated. Thus monocyanoethylation of 4-methoxybenzylamine followed by treatment with 4-chlorobutyronitrile gave the dinitrile N-(2-cyanoethyl)-...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2001
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236396/ http://dx.doi.org/10.3390/60300230 |