Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands

The synthesis of a series of new n-propyl and n-butyl chain containing 1-aryl-piperazine derivatives of quinazolidin-4(3H)-one (7) 2-phenyl-2,3-dihydrophthalazine-1,4-dione (8) and 1-phenyl-1,2-dihydropyridazine-3,6-dione (9) as potential serotonin receptor ligands is described.

Detalles Bibliográficos
Autores principales: Kowalski, Piotr, Kowalska, Teresa, Mokrosz, Maria J., Bojarski, Andrzej J., Charakchieva-Minol, Sijka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236407/
http://dx.doi.org/10.3390/60900784
_version_ 1783371028477509632
author Kowalski, Piotr
Kowalska, Teresa
Mokrosz, Maria J.
Bojarski, Andrzej J.
Charakchieva-Minol, Sijka
author_facet Kowalski, Piotr
Kowalska, Teresa
Mokrosz, Maria J.
Bojarski, Andrzej J.
Charakchieva-Minol, Sijka
author_sort Kowalski, Piotr
collection PubMed
description The synthesis of a series of new n-propyl and n-butyl chain containing 1-aryl-piperazine derivatives of quinazolidin-4(3H)-one (7) 2-phenyl-2,3-dihydrophthalazine-1,4-dione (8) and 1-phenyl-1,2-dihydropyridazine-3,6-dione (9) as potential serotonin receptor ligands is described.
format Online
Article
Text
id pubmed-6236407
institution National Center for Biotechnology Information
language English
publishDate 2001
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-62364072018-11-19 Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands Kowalski, Piotr Kowalska, Teresa Mokrosz, Maria J. Bojarski, Andrzej J. Charakchieva-Minol, Sijka Molecules Article The synthesis of a series of new n-propyl and n-butyl chain containing 1-aryl-piperazine derivatives of quinazolidin-4(3H)-one (7) 2-phenyl-2,3-dihydrophthalazine-1,4-dione (8) and 1-phenyl-1,2-dihydropyridazine-3,6-dione (9) as potential serotonin receptor ligands is described. MDPI 2001-08-31 /pmc/articles/PMC6236407/ http://dx.doi.org/10.3390/60900784 Text en © 2001 by MDPI (http://www.mdpi.org). Reproduction is permitted for noncommercial purposes.
spellingShingle Article
Kowalski, Piotr
Kowalska, Teresa
Mokrosz, Maria J.
Bojarski, Andrzej J.
Charakchieva-Minol, Sijka
Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title_full Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title_fullStr Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title_full_unstemmed Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title_short Biologically Active 1-Arylpiperazines. Synthesis of New N-(4-Aryl-1-piperazinyl)alkyl Derivatives of Quinazolidin-4(3H)-one, 2,3-Dihydrophthalazine-1,4-dione and 1,2-Dihydropyridazine-3,6-dione as Potential Serotonin Receptor Ligands
title_sort biologically active 1-arylpiperazines. synthesis of new n-(4-aryl-1-piperazinyl)alkyl derivatives of quinazolidin-4(3h)-one, 2,3-dihydrophthalazine-1,4-dione and 1,2-dihydropyridazine-3,6-dione as potential serotonin receptor ligands
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236407/
http://dx.doi.org/10.3390/60900784
work_keys_str_mv AT kowalskipiotr biologicallyactive1arylpiperazinessynthesisofnewn4aryl1piperazinylalkylderivativesofquinazolidin43hone23dihydrophthalazine14dioneand12dihydropyridazine36dioneaspotentialserotoninreceptorligands
AT kowalskateresa biologicallyactive1arylpiperazinessynthesisofnewn4aryl1piperazinylalkylderivativesofquinazolidin43hone23dihydrophthalazine14dioneand12dihydropyridazine36dioneaspotentialserotoninreceptorligands
AT mokroszmariaj biologicallyactive1arylpiperazinessynthesisofnewn4aryl1piperazinylalkylderivativesofquinazolidin43hone23dihydrophthalazine14dioneand12dihydropyridazine36dioneaspotentialserotoninreceptorligands
AT bojarskiandrzejj biologicallyactive1arylpiperazinessynthesisofnewn4aryl1piperazinylalkylderivativesofquinazolidin43hone23dihydrophthalazine14dioneand12dihydropyridazine36dioneaspotentialserotoninreceptorligands
AT charakchievaminolsijka biologicallyactive1arylpiperazinessynthesisofnewn4aryl1piperazinylalkylderivativesofquinazolidin43hone23dihydrophthalazine14dioneand12dihydropyridazine36dioneaspotentialserotoninreceptorligands

Ejemplares similares