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Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat

CASE SUMMARY: A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity. MRI of the head revealed an expansile soft tissue mass in the caudal nasal...

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Autores principales: Santifort, Koen M, Jurgens, Ben, Grinwis, Guy CM, Gielen, Ingrid, Meij, Björn P, Mandigers, Paul JJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236490/
https://www.ncbi.nlm.nih.gov/pubmed/30450218
http://dx.doi.org/10.1177/2055116918811179
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author Santifort, Koen M
Jurgens, Ben
Grinwis, Guy CM
Gielen, Ingrid
Meij, Björn P
Mandigers, Paul JJ
author_facet Santifort, Koen M
Jurgens, Ben
Grinwis, Guy CM
Gielen, Ingrid
Meij, Björn P
Mandigers, Paul JJ
author_sort Santifort, Koen M
collection PubMed
description CASE SUMMARY: A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity. MRI of the head revealed an expansile soft tissue mass in the caudal nasal passages (both sides but predominantly right-sided) involving the ethmoid bone and extending through the cribriform plate into the cranial vault affecting predominantly the right frontal lobe and temporal lobe. Histopathological examination of the tumour revealed a histiocytic sarcoma. RELEVANCE AND NOVEL INFORMATION: This is the first report of a cat with clinical signs of temporal lobe epilepsy due to an invasive, histiocytic sarcoma. Histiocytic sarcoma, although rare, should be included in the list of differential diagnoses for soft tissue masses extending through the cribriform plate. Other differential diagnoses are primary nasal neoplasia (eg, adenocarcinoma, squamous cell carcinoma, chondrosarcoma and other types of sarcomas), lymphoma and olfactory neuroblastoma. Temporal lobe epilepsy in cats can be the consequence of primary pathology of temporal lobe structures, or it can be a consequence of pathology with an effect on these structures (eg, mass effect or disruption of interconnecting neuronal pathways).
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spelling pubmed-62364902018-11-16 Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat Santifort, Koen M Jurgens, Ben Grinwis, Guy CM Gielen, Ingrid Meij, Björn P Mandigers, Paul JJ JFMS Open Rep Case Report CASE SUMMARY: A 10-year-old neutered female domestic shorthair cat was presented with an acute onset of neurological signs suggestive of a right-sided forebrain lesion, temporal lobe epilepsy and generalised seizure activity. MRI of the head revealed an expansile soft tissue mass in the caudal nasal passages (both sides but predominantly right-sided) involving the ethmoid bone and extending through the cribriform plate into the cranial vault affecting predominantly the right frontal lobe and temporal lobe. Histopathological examination of the tumour revealed a histiocytic sarcoma. RELEVANCE AND NOVEL INFORMATION: This is the first report of a cat with clinical signs of temporal lobe epilepsy due to an invasive, histiocytic sarcoma. Histiocytic sarcoma, although rare, should be included in the list of differential diagnoses for soft tissue masses extending through the cribriform plate. Other differential diagnoses are primary nasal neoplasia (eg, adenocarcinoma, squamous cell carcinoma, chondrosarcoma and other types of sarcomas), lymphoma and olfactory neuroblastoma. Temporal lobe epilepsy in cats can be the consequence of primary pathology of temporal lobe structures, or it can be a consequence of pathology with an effect on these structures (eg, mass effect or disruption of interconnecting neuronal pathways). SAGE Publications 2018-11-08 /pmc/articles/PMC6236490/ /pubmed/30450218 http://dx.doi.org/10.1177/2055116918811179 Text en © The Author(s) 2018 http://www.creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Santifort, Koen M
Jurgens, Ben
Grinwis, Guy CM
Gielen, Ingrid
Meij, Björn P
Mandigers, Paul JJ
Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title_full Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title_fullStr Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title_full_unstemmed Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title_short Invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
title_sort invasive nasal histiocytic sarcoma as a cause of temporal lobe epilepsy in a cat
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236490/
https://www.ncbi.nlm.nih.gov/pubmed/30450218
http://dx.doi.org/10.1177/2055116918811179
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