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Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study

BACKGROUND: Leptospirosis is a zoonotic disease associated with occupations which exposed workers to environments contaminated with urine of infected animals. The objective of this study was to determine the seroprevalence of leptospirosis among wet market workers in Kelantan. METHODS: A cross secti...

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Autores principales: Rahman, Mas Harithulfadhli Agus Ab, Hairon, Suhaily Mohd, Hamat, Rukman Awang, Jamaluddin, Tengku Zetty Maztura Tengku, Shafei, Mohd Nazri, Idris, Norazlin, Osman, Malina, Sukeri, Surianti, Wahab, Zainudin A., Mohammad, Wan Mohd Zahiruddin Wan, Idris, Zawaha, Daud, Aziah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236877/
https://www.ncbi.nlm.nih.gov/pubmed/30428852
http://dx.doi.org/10.1186/s12879-018-3470-5
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author Rahman, Mas Harithulfadhli Agus Ab
Hairon, Suhaily Mohd
Hamat, Rukman Awang
Jamaluddin, Tengku Zetty Maztura Tengku
Shafei, Mohd Nazri
Idris, Norazlin
Osman, Malina
Sukeri, Surianti
Wahab, Zainudin A.
Mohammad, Wan Mohd Zahiruddin Wan
Idris, Zawaha
Daud, Aziah
author_facet Rahman, Mas Harithulfadhli Agus Ab
Hairon, Suhaily Mohd
Hamat, Rukman Awang
Jamaluddin, Tengku Zetty Maztura Tengku
Shafei, Mohd Nazri
Idris, Norazlin
Osman, Malina
Sukeri, Surianti
Wahab, Zainudin A.
Mohammad, Wan Mohd Zahiruddin Wan
Idris, Zawaha
Daud, Aziah
author_sort Rahman, Mas Harithulfadhli Agus Ab
collection PubMed
description BACKGROUND: Leptospirosis is a zoonotic disease associated with occupations which exposed workers to environments contaminated with urine of infected animals. The objective of this study was to determine the seroprevalence of leptospirosis among wet market workers in Kelantan. METHODS: A cross sectional study was conducted in two main wet markets in Kelantan and 232 wet market workers were randomly selected. Blood samples were analysed for microscopic agglutination test (MAT) against 20 live leptospirosis reference serovars. MAT titres of 1:100 or more were considered as seropositive. RESULTS: It was found that the overall seroprevalence for leptospirosis among the respondents was 33.6% (95% CI = 27.5, 39.7). The samples were tested positive against serovars Melaka (IMR LEP 1), Terengganu (IMR LEP 115), Sarawak (IMR LEP 175), Copenhageni (IMR LEP 803/11), Hardjobovis (IMR LEP 27), Australis, Autumnalis, Bataviae, Canicola, Grippotyphosa, Hardjoprajitno, Icterohaemorrhagiae, Javanica, Pyrogenes, Terrasovi, Djasiman, Patoc and Pomona. The predominant serovars was Autumnalis (18.2%). CONCLUSION: Wet markets workers were at risk for leptospirosis infection evidenced by high seroprevalence of leptospirosis in this study. Further research need to be conducted to determine factors that favours infection in this groups.
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spelling pubmed-62368772018-11-20 Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study Rahman, Mas Harithulfadhli Agus Ab Hairon, Suhaily Mohd Hamat, Rukman Awang Jamaluddin, Tengku Zetty Maztura Tengku Shafei, Mohd Nazri Idris, Norazlin Osman, Malina Sukeri, Surianti Wahab, Zainudin A. Mohammad, Wan Mohd Zahiruddin Wan Idris, Zawaha Daud, Aziah BMC Infect Dis Research Article BACKGROUND: Leptospirosis is a zoonotic disease associated with occupations which exposed workers to environments contaminated with urine of infected animals. The objective of this study was to determine the seroprevalence of leptospirosis among wet market workers in Kelantan. METHODS: A cross sectional study was conducted in two main wet markets in Kelantan and 232 wet market workers were randomly selected. Blood samples were analysed for microscopic agglutination test (MAT) against 20 live leptospirosis reference serovars. MAT titres of 1:100 or more were considered as seropositive. RESULTS: It was found that the overall seroprevalence for leptospirosis among the respondents was 33.6% (95% CI = 27.5, 39.7). The samples were tested positive against serovars Melaka (IMR LEP 1), Terengganu (IMR LEP 115), Sarawak (IMR LEP 175), Copenhageni (IMR LEP 803/11), Hardjobovis (IMR LEP 27), Australis, Autumnalis, Bataviae, Canicola, Grippotyphosa, Hardjoprajitno, Icterohaemorrhagiae, Javanica, Pyrogenes, Terrasovi, Djasiman, Patoc and Pomona. The predominant serovars was Autumnalis (18.2%). CONCLUSION: Wet markets workers were at risk for leptospirosis infection evidenced by high seroprevalence of leptospirosis in this study. Further research need to be conducted to determine factors that favours infection in this groups. BioMed Central 2018-11-14 /pmc/articles/PMC6236877/ /pubmed/30428852 http://dx.doi.org/10.1186/s12879-018-3470-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Rahman, Mas Harithulfadhli Agus Ab
Hairon, Suhaily Mohd
Hamat, Rukman Awang
Jamaluddin, Tengku Zetty Maztura Tengku
Shafei, Mohd Nazri
Idris, Norazlin
Osman, Malina
Sukeri, Surianti
Wahab, Zainudin A.
Mohammad, Wan Mohd Zahiruddin Wan
Idris, Zawaha
Daud, Aziah
Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title_full Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title_fullStr Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title_full_unstemmed Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title_short Seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, Malaysia: a cross sectional study
title_sort seroprevalence and distribution of leptospirosis serovars among wet market workers in northeastern, malaysia: a cross sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236877/
https://www.ncbi.nlm.nih.gov/pubmed/30428852
http://dx.doi.org/10.1186/s12879-018-3470-5
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