Highly clarithromycin-resistant Helicobacter pylori infection in asymptomatic children from a rural community of Cajamarca-Peru

OBJECTIVE: The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). RESULTS: Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption th...

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Detalles Bibliográficos
Autores principales: Aguilar-Luis, Miguel Angel, Palacios-Cuervo, Fernando, Espinal-Reyes, Fátima, Calderón-Rivera, Andrea, Levy-Blitchtein, Saúl, Palomares-Reyes, Carlos, Silva-Caso, Wilmer, Zavaleta-Gavidia, Victor, Bazán-Mayra, Jorge, Cornejo-Tapia, Angela, del Valle-Mendoza, Juana, del Valle, Luis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236992/
https://www.ncbi.nlm.nih.gov/pubmed/30428917
http://dx.doi.org/10.1186/s13104-018-3919-z
Descripción
Sumario:OBJECTIVE: The objective of this study was to determine the prevalence of clarithromycin-resistant Helicobacter pylori in asymptomatic children in a rural community of Cajamarca (northern Peru). RESULTS: Helicobacter pylori was detected in 17.2% (49/285) of the samples. Unboiled water consumption the most frequent associated factor in patients with positive PCR for H. pylori infection (93.9%). Clarithromycin resistant mutations were found in 79.6% (39/49) of the positive samples for H. pylori. The most frequent mutation was A2142G (46.9%), followed by the double-mutation A2142G–A2143G (28.6%).

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