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Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty

PURPOSE: To examine the impact of graft thickness (GT) on postoperative visual acuity and endothelial cell density after ultrathin-Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus conventional DSAEK. METHODS: The medical records of all patients who underwent DSAEK at our insti...

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Autores principales: Droutsas, Konstantinos, Petrelli, Myrsini, Miltsakakis, Dimitrios, Andreanos, Konstantinos, Karagianni, Anastasia, Lazaridis, Apostolos, Koutsandrea, Chrysanthi, Kymionis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237014/
https://www.ncbi.nlm.nih.gov/pubmed/30515318
http://dx.doi.org/10.1155/2018/5924058
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author Droutsas, Konstantinos
Petrelli, Myrsini
Miltsakakis, Dimitrios
Andreanos, Konstantinos
Karagianni, Anastasia
Lazaridis, Apostolos
Koutsandrea, Chrysanthi
Kymionis, George
author_facet Droutsas, Konstantinos
Petrelli, Myrsini
Miltsakakis, Dimitrios
Andreanos, Konstantinos
Karagianni, Anastasia
Lazaridis, Apostolos
Koutsandrea, Chrysanthi
Kymionis, George
author_sort Droutsas, Konstantinos
collection PubMed
description PURPOSE: To examine the impact of graft thickness (GT) on postoperative visual acuity and endothelial cell density after ultrathin-Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus conventional DSAEK. METHODS: The medical records of all patients who underwent DSAEK at our institute during a 2-year period were reviewed. After excluding subjects with low visual potential, 34 eyes were divided into two groups based on the postoperative GT as measured with anterior segment optical coherence tomography (AS-OCT): an UT-DSAEK group (GT ≤ 100 μm, n=13 eyes) and a DSAEK group (GT > 100 μm, n=21 eyes). The groups were compared with regard to best-corrected visual acuity (BCVA), subjective refraction, central corneal thickness (CCT), GT, and endothelial cell density (ECD). RESULTS: Preoperative BCVA (logMAR) was 1.035 ± 0.514 and 0.772 ± 0.428 for UT-DSAEK and DSAEK, respectively (P=0.072). At 6 months postoperatively, BCVA was 0.088 ± 0.150 following UT-DSAEK and 0.285 ± 0.158 following DSAEK (P=0.001). CONCLUSION: DSAEK grafts with a thickness under 100 μm offered better visual outcomes during the early postoperative period.
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spelling pubmed-62370142018-12-04 Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty Droutsas, Konstantinos Petrelli, Myrsini Miltsakakis, Dimitrios Andreanos, Konstantinos Karagianni, Anastasia Lazaridis, Apostolos Koutsandrea, Chrysanthi Kymionis, George J Ophthalmol Research Article PURPOSE: To examine the impact of graft thickness (GT) on postoperative visual acuity and endothelial cell density after ultrathin-Descemet stripping automated endothelial keratoplasty (UT-DSAEK) versus conventional DSAEK. METHODS: The medical records of all patients who underwent DSAEK at our institute during a 2-year period were reviewed. After excluding subjects with low visual potential, 34 eyes were divided into two groups based on the postoperative GT as measured with anterior segment optical coherence tomography (AS-OCT): an UT-DSAEK group (GT ≤ 100 μm, n=13 eyes) and a DSAEK group (GT > 100 μm, n=21 eyes). The groups were compared with regard to best-corrected visual acuity (BCVA), subjective refraction, central corneal thickness (CCT), GT, and endothelial cell density (ECD). RESULTS: Preoperative BCVA (logMAR) was 1.035 ± 0.514 and 0.772 ± 0.428 for UT-DSAEK and DSAEK, respectively (P=0.072). At 6 months postoperatively, BCVA was 0.088 ± 0.150 following UT-DSAEK and 0.285 ± 0.158 following DSAEK (P=0.001). CONCLUSION: DSAEK grafts with a thickness under 100 μm offered better visual outcomes during the early postoperative period. Hindawi 2018-11-01 /pmc/articles/PMC6237014/ /pubmed/30515318 http://dx.doi.org/10.1155/2018/5924058 Text en Copyright © 2018 Konstantinos Droutsas et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Droutsas, Konstantinos
Petrelli, Myrsini
Miltsakakis, Dimitrios
Andreanos, Konstantinos
Karagianni, Anastasia
Lazaridis, Apostolos
Koutsandrea, Chrysanthi
Kymionis, George
Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title_full Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title_fullStr Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title_full_unstemmed Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title_short Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
title_sort visual outcomes of ultrathin-descemet stripping endothelial keratoplasty versus descemet stripping endothelial keratoplasty
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237014/
https://www.ncbi.nlm.nih.gov/pubmed/30515318
http://dx.doi.org/10.1155/2018/5924058
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