proBDNF is modified by advanced glycation end products in Alzheimer’s disease and causes neuronal apoptosis by inducing p75 neurotrophin receptor processing

Alzheimer disease (AD) is a complex pathology related to multiple causes including oxidative stress. Brain-derived neurotrophic factor (BDNF) is a neutrotrophic factor essential for the survival and differentiation of neurons and is considered a key target in the pathophysiology of various neurodege...

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Detalles Bibliográficos
Autores principales: Fleitas, Catherine, Piñol-Ripoll, Gerard, Marfull, Pau, Rocandio, Daniel, Ferrer, Isidro, Rampon, Claire, Egea, Joaquim, Espinet, Carme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237019/
https://www.ncbi.nlm.nih.gov/pubmed/30428894
http://dx.doi.org/10.1186/s13041-018-0411-6

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