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Genetic polymorphism of the methotrexate transporter ABCG2, blood pressure and markers of arterial function in patients with rheumatoid arthritis: repeated cross-sectional study

PURPOSE: Methotrexate (MTX) treatment is associated with lower blood pressure (BP) and arterial stiffness in rheumatoid arthritis (RA). We investigated associations between single-nucleotide polymorphism (SNP) of the ATP-binding cassette efflux transporter gene ABCG2 (rs2231142), BP, and arterial st...

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Detalles Bibliográficos
Autores principales: Baghdadi, Leena R, Woodman, Richard J, Shanahan, E Michael, Wiese, Michael D, Mangoni, Arduino A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237132/
https://www.ncbi.nlm.nih.gov/pubmed/30519074
http://dx.doi.org/10.2147/PGPM.S170557

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