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CTL019 (tisagenlecleucel): CAR-T therapy for relapsed and refractory B-cell acute lymphoblastic leukemia

Over the past decades, survival of patients with acute lymphoblastic leukemia (ALL) has dramatically improved, but the subgroup of patients with relapsed/refractory ALL still continues to have dismal prognosis. As an emerging therapeutic approach, chimeric antigen receptor-modified T-cells (CAR-T) r...

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Detalles Bibliográficos
Autores principales:	Vairy, Stephanie, Garcia, Julia Lopes, Teira, Pierre, Bittencourt, Henrique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237143/ https://www.ncbi.nlm.nih.gov/pubmed/30518999 http://dx.doi.org/10.2147/DDDT.S138765

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