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Synthesis of novel 6,7-dimethoxy-4-anilinoquinolines as potent c-Met inhibitors

HGF/c-Met signalling pathway plays an important role in the development of cancers. A series of 6,7-dimethoxy-4-anilinoquinolines possessing benzimidazole moiety were synthesised and identified as potent inhibitors of the tyrosine kinase c-Met. Their in vitro biological activities against three canc...

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Detalles Bibliográficos
Autores principales:	Zhang, Qing-Wen, Ye, Zi-Dan, Shen, Chang, Tie, Hong-Xia, Wang, Lei, Shi, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Short Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237173/ https://www.ncbi.nlm.nih.gov/pubmed/30422010 http://dx.doi.org/10.1080/14756366.2018.1533822

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