Cargando…
Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa
PURPOSE: The I307N rhodopsin (Rho) mouse is a light-inducible model of autosomal dominant retinitis pigmentosa (adRP) that may be useful in testing therapies. We investigated the time-course of retinal changes of the I307N Rho mouse with spectral-domain optical coherence tomography (SD-OCT). METHODS...
Autores principales: | Massengill, Michael T., Young, Brianna, Patel, Deep, Jafri, Farwa, Sabogal, Ernesto, Ash, Neil, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237214/ https://www.ncbi.nlm.nih.gov/pubmed/30452595 http://dx.doi.org/10.1167/iovs.18-25345 |
Ejemplares similares
-
Gene Therapy for Rhodopsin-associated Autosomal Dominant Retinitis Pigmentosa
por: Massengill, Michael T., et al.
Publicado: (2021) -
Sectoral activation of glia in an inducible mouse model of autosomal dominant retinitis pigmentosa
por: Massengill, Michael T., et al.
Publicado: (2020) -
Complexity of the Class B Phenotype in Autosomal Dominant Retinitis Pigmentosa Due to Rhodopsin Mutations
por: Jacobson, Samuel G., et al.
Publicado: (2016) -
Inner retinal preservation in the photoinducible I307N rhodopsin mutant mouse, a model of autosomal dominant retinitis pigmentosa
por: Stefanov, Antonia, et al.
Publicado: (2019) -
Wheel running exercise protects against retinal degeneration in the I307N rhodopsin mouse model of inducible autosomal dominant retinitis pigmentosa
por: Zhang, Xian, et al.
Publicado: (2019)