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Clinically Relevant Outcome Measures for the I307N Rhodopsin Mouse: A Model of Inducible Autosomal Dominant Retinitis Pigmentosa

PURPOSE: The I307N rhodopsin (Rho) mouse is a light-inducible model of autosomal dominant retinitis pigmentosa (adRP) that may be useful in testing therapies. We investigated the time-course of retinal changes of the I307N Rho mouse with spectral-domain optical coherence tomography (SD-OCT). METHODS...

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Detalles Bibliográficos
Autores principales:	Massengill, Michael T., Young, Brianna, Patel, Deep, Jafri, Farwa, Sabogal, Ernesto, Ash, Neil, Li, Hong, Ildefonso, Cristhian J., Lewin, Alfred S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237214/ https://www.ncbi.nlm.nih.gov/pubmed/30452595 http://dx.doi.org/10.1167/iovs.18-25345

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