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Decrease in Plasma Membrane Tension Triggers PtdIns(4,5)P(2) Phase Separation to Inactivate TORC2
The Target of Rapamycin Complex 2 (TORC2) plays a key role in maintaining the homeostasis of plasma membrane (PM) tension. TORC2 activation upon increased PM tension involves redistribution of the Slm1 and 2 paralogs from PM invaginations known as eisosomes into membrane compartments containing TORC...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237274/ https://www.ncbi.nlm.nih.gov/pubmed/30154550 http://dx.doi.org/10.1038/s41556-018-0150-z |