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HIV cascade of care in Greece: Useful insights from additional stages
BACKGROUND: Aiming to eliminate HIV infection, UNAIDS has set a global “90-90-90” target by 2020. We sought to construct a 6-stages HIV Cascade of Care (CoC) in Greece, overall and by risk group, to assess risk-group and stage-specific progress in achieving the UNAIDS target. PATIENTS AND METHODS: C...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237384/ https://www.ncbi.nlm.nih.gov/pubmed/30440000 http://dx.doi.org/10.1371/journal.pone.0207355 |
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author | Vourli, Georgia Nikolopoulos, Georgios Paparizos, Vasilios Skoutelis, Athanasios Metallidis, Symeon Gargalianos, Panagiotis Papadopoulos, Antonios Chini, Maria Sipsas, Nikolaos V. Psychogiou, Mina Chrysos, Georgios Sambatakou, Helen Gogos, Charalambos Katsarou, Olga Paraskeva, Dimitra Dedes, Nikos Touloumi, Giota |
author_facet | Vourli, Georgia Nikolopoulos, Georgios Paparizos, Vasilios Skoutelis, Athanasios Metallidis, Symeon Gargalianos, Panagiotis Papadopoulos, Antonios Chini, Maria Sipsas, Nikolaos V. Psychogiou, Mina Chrysos, Georgios Sambatakou, Helen Gogos, Charalambos Katsarou, Olga Paraskeva, Dimitra Dedes, Nikos Touloumi, Giota |
author_sort | Vourli, Georgia |
collection | PubMed |
description | BACKGROUND: Aiming to eliminate HIV infection, UNAIDS has set a global “90-90-90” target by 2020. We sought to construct a 6-stages HIV Cascade of Care (CoC) in Greece, overall and by risk group, to assess risk-group and stage-specific progress in achieving the UNAIDS target. PATIENTS AND METHODS: Combining data from the HIV/AIDS surveillance system and a population-based HIV cohort study, the CoC included: i) number of people living with HIV (PLHIV) by end of 2013; ii) proportion of PLHIV ever diagnosed; iii) proportion of diagnosed linked-to-care iv) proportion of linked-to-care ever initiating antiretroviral therapy (ART); v) proportion of treated who retained-in-care vi) proportion of those retained-in-care who were virally suppressed (≤200 copies/mL) at their last visit (01/07/2012-31/12/2013). RESULTS: In 2013, 14147 PLHIV were in Greece. Overall, proportions of each stage in the cascade were: 78.4% diagnosed; 86% linked-to-care; 78.5% initiated ART; 86.4% retained-in-care, and 87.1% virally suppressed. Totally, 42.6% of all PLHIV were virally suppressed. The percentage diagnosed was lower among heterosexual men and women (heterosexuals) than in MSM (men who have sex with men) or PWID (people who inject drugs). Most MSM were linked to care (97.2% of diagnosed) while a substantial proportion of PWID were not (80.8% of diagnosed). Once treated, PWID remained in care in similar proportions to MSM. Unlike PWID, a high proportion of the retained in care MSM and heterosexuals achieved viral suppression. CONCLUSIONS: At the end of 2013, we identified gaps in the HIV CoC in Greece, which differed across risk groups. Targeted interventions are critical in optimizing early diagnosis and timely linkage. A 6-stage CoC, stratified by risk group, can inform strategic public health planning in improving HIV treatment outcomes. |
format | Online Article Text |
id | pubmed-6237384 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-62373842018-12-01 HIV cascade of care in Greece: Useful insights from additional stages Vourli, Georgia Nikolopoulos, Georgios Paparizos, Vasilios Skoutelis, Athanasios Metallidis, Symeon Gargalianos, Panagiotis Papadopoulos, Antonios Chini, Maria Sipsas, Nikolaos V. Psychogiou, Mina Chrysos, Georgios Sambatakou, Helen Gogos, Charalambos Katsarou, Olga Paraskeva, Dimitra Dedes, Nikos Touloumi, Giota PLoS One Research Article BACKGROUND: Aiming to eliminate HIV infection, UNAIDS has set a global “90-90-90” target by 2020. We sought to construct a 6-stages HIV Cascade of Care (CoC) in Greece, overall and by risk group, to assess risk-group and stage-specific progress in achieving the UNAIDS target. PATIENTS AND METHODS: Combining data from the HIV/AIDS surveillance system and a population-based HIV cohort study, the CoC included: i) number of people living with HIV (PLHIV) by end of 2013; ii) proportion of PLHIV ever diagnosed; iii) proportion of diagnosed linked-to-care iv) proportion of linked-to-care ever initiating antiretroviral therapy (ART); v) proportion of treated who retained-in-care vi) proportion of those retained-in-care who were virally suppressed (≤200 copies/mL) at their last visit (01/07/2012-31/12/2013). RESULTS: In 2013, 14147 PLHIV were in Greece. Overall, proportions of each stage in the cascade were: 78.4% diagnosed; 86% linked-to-care; 78.5% initiated ART; 86.4% retained-in-care, and 87.1% virally suppressed. Totally, 42.6% of all PLHIV were virally suppressed. The percentage diagnosed was lower among heterosexual men and women (heterosexuals) than in MSM (men who have sex with men) or PWID (people who inject drugs). Most MSM were linked to care (97.2% of diagnosed) while a substantial proportion of PWID were not (80.8% of diagnosed). Once treated, PWID remained in care in similar proportions to MSM. Unlike PWID, a high proportion of the retained in care MSM and heterosexuals achieved viral suppression. CONCLUSIONS: At the end of 2013, we identified gaps in the HIV CoC in Greece, which differed across risk groups. Targeted interventions are critical in optimizing early diagnosis and timely linkage. A 6-stage CoC, stratified by risk group, can inform strategic public health planning in improving HIV treatment outcomes. Public Library of Science 2018-11-15 /pmc/articles/PMC6237384/ /pubmed/30440000 http://dx.doi.org/10.1371/journal.pone.0207355 Text en © 2018 Vourli et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Vourli, Georgia Nikolopoulos, Georgios Paparizos, Vasilios Skoutelis, Athanasios Metallidis, Symeon Gargalianos, Panagiotis Papadopoulos, Antonios Chini, Maria Sipsas, Nikolaos V. Psychogiou, Mina Chrysos, Georgios Sambatakou, Helen Gogos, Charalambos Katsarou, Olga Paraskeva, Dimitra Dedes, Nikos Touloumi, Giota HIV cascade of care in Greece: Useful insights from additional stages |
title | HIV cascade of care in Greece: Useful insights from additional stages |
title_full | HIV cascade of care in Greece: Useful insights from additional stages |
title_fullStr | HIV cascade of care in Greece: Useful insights from additional stages |
title_full_unstemmed | HIV cascade of care in Greece: Useful insights from additional stages |
title_short | HIV cascade of care in Greece: Useful insights from additional stages |
title_sort | hiv cascade of care in greece: useful insights from additional stages |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237384/ https://www.ncbi.nlm.nih.gov/pubmed/30440000 http://dx.doi.org/10.1371/journal.pone.0207355 |
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