Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1

Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Poly(ADP-ribose) polymerase 1 (PARP1) regulates accessibility of chromatin, alters functions of transcriptional activators and repressors, an...

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Detalles Bibliográficos
Autores principales: Hulse, Michael, Caruso, Lisa B., Madzo, Jozef, Tan, Yinfei, Johnson, Sarah, Tempera, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237423/
https://www.ncbi.nlm.nih.gov/pubmed/30395643
http://dx.doi.org/10.1371/journal.ppat.1007394

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