Cargando…

MiR‐17 family‐mediated regulation of Pknox1 influences hepatic steatosis and insulin signaling

The aberrant expression of Pknox1 is associated with hepatic glucose and lipid dysmetabolism status of type 2 diabetes mellitus (T2DM) and nonalcoholic fatty liver disease (NAFLD). However, the underlying mechanism causing Pknox1 overexpression in this pathological status remains unclear. By using m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Dan, Lou, Guohua, Zhang, Tianbao, Dong, Fengqin, Liu, Yanning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237553/ https://www.ncbi.nlm.nih.gov/pubmed/30338914 http://dx.doi.org/10.1111/jcmm.13902

Ejemplares similares

Role of miR-223 in the pathophysiology of liver diseases
por: Ye, Dan, et al.
Publicado: (2018)

AMSC-derived exosomes alleviate lipopolysaccharide/d-galactosamine-induced acute liver failure by miR-17-mediated reduction of TXNIP/NLRP3 inflammasome activation in macrophages
por: Liu, Yanning, et al.
Publicado: (2018)

miR-19b-3p/PKNOX1 Regulates Viral Myocarditis by Regulating Macrophage Polarization
por: Jiahui, Chen, et al.
Publicado: (2022)

Inhibition of intervertebral disc disease progression via the circPKNOX1–miR-370-3p–KIAA0355 axis
por: Huang, Yizhen, et al.
Publicado: (2021)

miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis
por: Li, Yuan-yuan, et al.
Publicado: (2020)

miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1
por: Cheng, Xiao-Yu, et al.
Publicado: (2018)

MiR‐122 modification enhances the therapeutic efficacy of adipose tissue‐derived mesenchymal stem cells against liver fibrosis
por: Lou, Guohua, et al.
Publicado: (2017)

Bortezomib induced peripheral neuropathy and single nucleotide polymorphisms in PKNOX1
por: Zhou, Xiang, et al.
Publicado: (2023)

Hepatic miR-192-3p reactivation alleviates steatosis by targeting glucocorticoid receptor
por: Wang, Zhangting, et al.
Publicado: (2020)

MiR‐22 modulates the expression of lipogenesis‐related genes and promotes hepatic steatosis in vitro
por: Yang, Zhuo, et al.
Publicado: (2020)

MiRNA-17 encoded by the miR-17-92 cluster increases the potential for steatosis in hepatoma cells by targeting CYP7A1
por: Gong, Ruijie, et al.
Publicado: (2018)

lncRNA MALAT1 modulates cancer stem cell properties of liver cancer cells by regulating YAP1 expression via miR-375 sponging
por: Zhao, Liying, et al.
Publicado: (2020)

miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster
por: Sweat, Yan, et al.
Publicado: (2021)

Modulation of liver steatosis by miR-21/PPARα
por: Rodrigues, Pedro M., et al.
Publicado: (2018)

Haplotype Distribution and Evolutionary Pattern of miR-17 and miR-124 Families Based on Population Analysis
por: Guo, Li, et al.
Publicado: (2009)

MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension
por: Nandakumar, Priyanka, et al.
Publicado: (2017)

Hepatic steatosis does not cause insulin resistance in people with familial hypobetalipoproteinaemia
por: Visser, M. E., et al.
Publicado: (2011)

miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction
por: Hu, Ying, et al.
Publicado: (2020)

Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
por: Lou, Guohua, et al.
Publicado: (2015)

MiR-144-3p-mediated dysregulation of EIF4G2 contributes to the development of hepatocellular carcinoma through the ERK pathway
por: Li, Shuangshuang, et al.
Publicado: (2021)

Semaglutide May Alleviate Hepatic Steatosis in T2DM Combined with NFALD Mice via miR-5120/ABHD6
por: Li, Ran, et al.
Publicado: (2022)

miR-93, miR-373, and miR-17-5p Negatively Regulate the Expression of TBP2 in Lung Cancer
por: Li, Ye, et al.
Publicado: (2020)

Anti-microRNA screen uncovers miR-17 family within miR-17~92 cluster as the primary driver of kidney cyst growth
por: Yheskel, Matanel, et al.
Publicado: (2019)

Hepatic miR-215 target Rictor and modulation of hepatic insulin signalling in rats
por: Li, Wei-Dong, et al.
Publicado: (2019)

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging
por: Hackl, Matthias, et al.
Publicado: (2010)

Direct targeting sperm-associated antigen 9 by miR-141 influences hepatocellular carcinoma cell growth and metastasis via JNK pathway
por: Lou, Guohua, et al.
Publicado: (2016)

Insulin resistance, steatosis and hepatitis C virus
por: Mangia, Alessandra, et al.
Publicado: (2013)

Hepatitis C Virus, Insulin Resistance, and Steatosis
por: Kralj, Dominik, et al.
Publicado: (2016)

SRSF3 shapes the structure of miR‐17‐92 cluster RNA and promotes selective processing of miR‐17 and miR‐20a
por: Ratnadiwakara, Madara, et al.
Publicado: (2023)

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development
por: Zindy, Frederique, et al.
Publicado: (2014)

The regulatory and predictive functions of miR-17 and miR-92 families on cisplatin resistance of non-small cell lung cancer
por: Zhao, Jian, et al.
Publicado: (2015)

PKNOX2 suppresses gastric cancer through the transcriptional activation of IGFBP5 and p53
por: Zhang, Li, et al.
Publicado: (2019)

Accelerated Evolution Analysis Uncovers PKNOX2 as a Key Transcription Factor in the Mammalian Cochlea
por: Trigila, Anabella P, et al.
Publicado: (2023)

The Combination of Berberine, Tocotrienols and Coffee Extracts Improves Metabolic Profile and Liver Steatosis by the Modulation of Gut Microbiota and Hepatic miR-122 and miR-34a Expression in Mice
por: Cossiga, Valentina, et al.
Publicado: (2021)

MiR-192, miR-200c and miR-17 are fibroblast-mediated inhibitors of colorectal cancer invasion
por: Ast, Volker, et al.
Publicado: (2018)

Hepatic deficiency of selenoprotein S exacerbates hepatic steatosis and insulin resistance
por: Qiao, Lu, et al.
Publicado: (2022)

miR-21, miR-17 and miR-19a induced by phosphatase of regenerating liver-3 promote the proliferation and metastasis of colon cancer
por: Zhang, J, et al.
Publicado: (2012)

Circulating miR-17, miR-20a, miR-29c, and miR-223 Combined as Non-Invasive Biomarkers in Nasopharyngeal Carcinoma
por: Zeng, Xi, et al.
Publicado: (2012)

MiR-17 and miR-19 cooperatively promote skeletal muscle cell differentiation
por: Kong, Delin, et al.
Publicado: (2019)

MiR-15b can target insulin receptor to regulate hepatic insulin signaling in mice
por: Li, Wei-Dong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2alp8tfs3ig66f8qdi7kg4s43k