Identification of Lynch syndrome risk variants in the Romanian population

Two familial forms of colorectal cancer (CRC), Lynch syndrome (LS) and familial adenomatous polyposis (FAP), are caused by rare mutations in DNA mismatch repair genes (MLH1,MSH2,MSH6,PMS2) and the genes APC and MUTYH, respectively. No information is available on the presence of high‐risk CRC mutatio...

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Detalles Bibliográficos
Autores principales: Iordache, Paul D., Mates, Dana, Gunnarsson, Bjarni, Eggertsson, Hannes P., Sulem, Patrick, Benonisdottir, Stefania, Csiki, Irma Eva, Rascu, Stefan, Radavoi, Daniel, Ursu, Radu, Staicu, Catalin, Calota, Violeta, Voinoiu, Angelica, Jinga, Mariana, Rosoga, Gabriel, Danau, Razvan, Sima, Sorin Cristian, Badescu, Daniel, Suciu, Nicoleta, Radoi, Viorica, Mates, Ioan Nicolae, Dobra, Mihai, Nicolae, Camelia, Kristjansdottir, Sigrun, Jonasson, Jon G., Manolescu, Andrei, Arnadottir, Gudny, Jensson, Brynjar, Jonasdottir, Aslaug, Sigurdsson, Asgeir, le Roux, Louise, Johannsdottir, Hrefna, Rafnar, Thorunn, Halldorsson, Bjarni V., Jinga, Viorel, Stefansson, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237568/
https://www.ncbi.nlm.nih.gov/pubmed/30324682
http://dx.doi.org/10.1111/jcmm.13881

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