Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts

Increasing evidence highlights that senescence plays an important role in idiopathic pulmonary fibrosis (IPF). This study delineates the specific contribution of mitochondria and the superoxide they form to the senescent phenotype of lung fibroblasts from IPF patients (IPF‐LFs). Primary cultures of...

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Detalles Bibliográficos
Autores principales: Schuliga, Michael, Pechkovsky, Dmitri V, Read, Jane, Waters, David W, Blokland, Kaj E C, Reid, Andrew T, Hogaboam, Cory M, Khalil, Nasreen, Burgess, Janette K, Prêle, Cecilia M, Mutsaers, Steven E, Jaffar, Jade, Westall, Glen, Grainge, Christopher, Knight, Darryl A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237609/
https://www.ncbi.nlm.nih.gov/pubmed/30255990
http://dx.doi.org/10.1111/jcmm.13855

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