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PLK1 targets CtIP to promote microhomology-mediated end joining

Proper DNA double-strand break (DSB) repair is essential for maintaining genome integrity. Microhomology-mediated end joining (MMEJ) is an error-prone repair mechanism, which introduces mutations at break sites and contributes to chromosomal translocations and telomere fusions, thus driving carcinog...

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Detalles Bibliográficos
Autores principales:	Wang, Hailong, Qiu, Zhiyu, Liu, Bo, Wu, Yan, Ren, Jianping, Liu, Yaqing, Zhao, Yuqin, Wang, Ya, Hao, Shuailin, Li, Zheng, Peng, Bin, Xu, Xingzhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237753/ https://www.ncbi.nlm.nih.gov/pubmed/30202980 http://dx.doi.org/10.1093/nar/gky810

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