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Disentangling transcription factor binding site complexity
The binding motifs of many transcription factors (TFs) comprise a higher degree of complexity than a single position weight matrix model permits. Additional complexity is typically taken into account either as intra-motif dependencies via more sophisticated probabilistic models or as heterogeneities...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237759/ https://www.ncbi.nlm.nih.gov/pubmed/30085218 http://dx.doi.org/10.1093/nar/gky683 |