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How to fold and protect mitochondrial ribosomal RNA with fewer guanines

Mammalian mitochondrial ribosomes evolved from bacterial ribosomes by reduction of ribosomal RNAs, increase of ribosomal protein content, and loss of guanine nucleotides. Guanine is the base most sensitive to oxidative damage. By systematically comparing high-quality, small ribosomal subunit RNA seq...

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Detalles Bibliográficos
Autores principales: Hosseini, Maryam, Roy, Poorna, Sissler, Marie, Zirbel, Craig L, Westhof, Eric, Leontis, Neocles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237812/
https://www.ncbi.nlm.nih.gov/pubmed/30215760
http://dx.doi.org/10.1093/nar/gky762