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ISGF3 with reduced phosphorylation is associated with constitutive expression of interferon-induced genes in aging cells
During cellular aging, many changes in cellular functions occur. A hallmark of aged cells is secretion of inflammatory mediators, which collectively is referred to as the senescence-associated secretory phenotype (SASP). However, the mechanisms underlying such changes are unclear. Canonically, the e...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237867/ https://www.ncbi.nlm.nih.gov/pubmed/30455980 http://dx.doi.org/10.1038/s41514-018-0030-6 |