The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain

The homeostasis of the proteome depends on the tight regulation of the mRNA and protein abundances, of the translation rates, and of the protein lifetimes. Results from several studies on prokaryotes or eukaryotic cell cultures have suggested that protein homeostasis is connected to, and perhaps reg...

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Detalles Bibliográficos
Autores principales: Mandad, Sunit, Rahman, Raza-Ur, Centeno, Tonatiuh Pena, Vidal, Ramon O., Wildhagen, Hanna, Rammner, Burkhard, Keihani, Sarva, Opazo, Felipe, Urban, Inga, Ischebeck, Till, Kirli, Koray, Benito, Eva, Fischer, André, Yousefi, Roya Y., Dennerlein, Sven, Rehling, Peter, Feussner, Ivo, Urlaub, Henning, Bonn, Stefan, Rizzoli, Silvio O., Fornasiero, Eugenio F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237891/
https://www.ncbi.nlm.nih.gov/pubmed/30443017
http://dx.doi.org/10.1038/s41598-018-35277-8

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