Clinical performance of an analytically validated assay in comparison to microarray technology to assess PITX2 DNA-methylation in breast cancer

Significant evidence has accumulated that DNA-methylation of the paired-like homeodomain transcription factor 2 (PITX2) gene can serve as a prognostic and predictive biomarker in breast cancer. PITX2 DNA-methylation data have been obtained so far from microarray and polymerase chain reaction (PCR)-b...

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Detalles Bibliográficos
Autores principales: Schricker, Gabriele, Napieralski, Rudolf, Noske, Aurelia, Piednoir, Elodie, Manner, Olivia, Schüren, Elisabeth, Lauber, Jürgen, Perkins, Jonathan, Magdolen, Viktor, Schmitt, Manfred, Ulm, Kurt, Weichert, Wilko, Kiechle, Marion, Martens, John W. M., Wilhelm, Olaf G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6237923/
https://www.ncbi.nlm.nih.gov/pubmed/30442983
http://dx.doi.org/10.1038/s41598-018-34919-1

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