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Classifying human promoters by occupancy patterns identifies recurring sequence elements, combinatorial binding, and spatial interactions

BACKGROUND: Characterizing recurring sequence patterns in human promoters has been a challenging undertaking even nowadays where a near-complete overview of promoters exists. However, with the more recent availability of genomic location (ChIP-seq) data, one can approach that question through the id...

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Detalles Bibliográficos
Autores principales: Yang, Xinyi, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238301/
https://www.ncbi.nlm.nih.gov/pubmed/30442124
http://dx.doi.org/10.1186/s12915-018-0585-5