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Preanalytical Variables and Their Influence on the Quality of Laboratory Results

While analytical standards have been developed by established quality control criteria, there has been a paucity in the development of standards for the preanalytical phase. Only recently recommendations have been published regarding the quality of samples including the definition of the optimal sam...

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Autores principales: Narayanan, Sheshadri, Guder, Walter G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Communications and Publications Division (CPD) of the IFCC 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238383/
https://www.ncbi.nlm.nih.gov/pubmed/30459536
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author Narayanan, Sheshadri
Guder, Walter G.
author_facet Narayanan, Sheshadri
Guder, Walter G.
author_sort Narayanan, Sheshadri
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description While analytical standards have been developed by established quality control criteria, there has been a paucity in the development of standards for the preanalytical phase. Only recently recommendations have been published regarding the quality of samples including the definition of the optimal sample size, the use of anticoagulants and stabilizers, stability criteria regarding transport and storage and handling of hemolytic, lipemic and icteric samples. Technical recommendations regarding sampling, transport and identification have been developed by national and international consensus organizations. The development of a preanalytical quality manual takes on an urgency in the goal towards achieving total quality control. Every day the laboratory is confronted with data arising out of preanalytical errors. Ability to recognize such data is critical to maintaining total laboratory quality and will be illustrated with case studies.
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spelling pubmed-62383832018-11-20 Preanalytical Variables and Their Influence on the Quality of Laboratory Results Narayanan, Sheshadri Guder, Walter G. EJIFCC Case Report While analytical standards have been developed by established quality control criteria, there has been a paucity in the development of standards for the preanalytical phase. Only recently recommendations have been published regarding the quality of samples including the definition of the optimal sample size, the use of anticoagulants and stabilizers, stability criteria regarding transport and storage and handling of hemolytic, lipemic and icteric samples. Technical recommendations regarding sampling, transport and identification have been developed by national and international consensus organizations. The development of a preanalytical quality manual takes on an urgency in the goal towards achieving total quality control. Every day the laboratory is confronted with data arising out of preanalytical errors. Ability to recognize such data is critical to maintaining total laboratory quality and will be illustrated with case studies. The Communications and Publications Division (CPD) of the IFCC 2001-04-05 /pmc/articles/PMC6238383/ /pubmed/30459536 Text en Copyright © 2001 International Federation of Clinical Chemistry and Laboratory Medicine (IFCC). All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Narayanan, Sheshadri
Guder, Walter G.
Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title_full Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title_fullStr Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title_full_unstemmed Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title_short Preanalytical Variables and Their Influence on the Quality of Laboratory Results
title_sort preanalytical variables and their influence on the quality of laboratory results
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238383/
https://www.ncbi.nlm.nih.gov/pubmed/30459536
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