Modeling hallmark pathology using motor neurons derived from the family and sporadic amyotrophic lateral sclerosis patient-specific iPS cells

BACKGROUND: Amyotrophic lateral sclerosis (ALS) represents a devastating, progressive, heterogeneous, and the most common motor neuron (MN) disease. To date, no cure has been available for the condition. Studies with transgenic mice have yielded significant results that help us understand the underl...

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Detalles Bibliográficos
Autores principales: Sun, Xuejiao, Song, Jianyuan, Huang, Hailong, Chen, Hong, Qian, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238404/
https://www.ncbi.nlm.nih.gov/pubmed/30442180
http://dx.doi.org/10.1186/s13287-018-1048-1

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