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LATS1 and LATS2 suppress breast cancer progression by maintaining cell identity and metabolic state

Deregulated activity of LArge Tumor Suppressor (LATS) tumor suppressors has broad implications on cellular and tissue homeostasis. We examined the consequences of down-regulation of either LATS1 or LATS2 in breast cancer. Consistent with their proposed tumor suppressive roles, expression of both par...

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Detalles Bibliográficos
Autores principales: Furth, Noa, Pateras, Ioannis S, Rotkopf, Ron, Vlachou, Vassiliki, Rivkin, Irina, Schmitt, Ina, Bakaev, Deborah, Gershoni, Anat, Ainbinder, Elena, Leshkowitz, Dena, Johnson, Randy L, Gorgoulis, Vassilis G, Oren, Moshe, Aylon, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238411/
https://www.ncbi.nlm.nih.gov/pubmed/30456386
http://dx.doi.org/10.26508/lsa.201800171