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Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)

Patient: Male, 49 Final Diagnosis: Hepatocellular carcinoma Symptoms: Abdominal pain Medication: — Clinical Procedure: Liver transplant Specialty: Transplantology OBJECTIVE: Unusual clinical course BACKGROUND: The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is...

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Autores principales: de Souza Martins Fernandes, Eduardo, de Mello, Felipe Pedreira Tavares, Andrade, Ronaldo Oliveira, Girao, Camila Liberato, Pimentel, Leandro Savattone, Cesar, Camilla, Sousa, Claudia Cristina, Brito-Azevedo, Anderson, Basto, Samanta Teixeira, Torres, Orlando Jorge Martins
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238545/
https://www.ncbi.nlm.nih.gov/pubmed/30409960
http://dx.doi.org/10.12659/AJCR.911694
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author de Souza Martins Fernandes, Eduardo
de Mello, Felipe Pedreira Tavares
Andrade, Ronaldo Oliveira
Girao, Camila Liberato
Pimentel, Leandro Savattone
Cesar, Camilla
Sousa, Claudia Cristina
Brito-Azevedo, Anderson
Basto, Samanta Teixeira
Torres, Orlando Jorge Martins
author_facet de Souza Martins Fernandes, Eduardo
de Mello, Felipe Pedreira Tavares
Andrade, Ronaldo Oliveira
Girao, Camila Liberato
Pimentel, Leandro Savattone
Cesar, Camilla
Sousa, Claudia Cristina
Brito-Azevedo, Anderson
Basto, Samanta Teixeira
Torres, Orlando Jorge Martins
author_sort de Souza Martins Fernandes, Eduardo
collection PubMed
description Patient: Male, 49 Final Diagnosis: Hepatocellular carcinoma Symptoms: Abdominal pain Medication: — Clinical Procedure: Liver transplant Specialty: Transplantology OBJECTIVE: Unusual clinical course BACKGROUND: The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is an important tool to induce fast liver hypertrophy. The degree of hepatic fibrosis/cirrhosis in patients with HCC negatively impacts their health, and the risk of liver failure is always present. In these cases, liver transplantation may be necessary as a rescue procedure. We present the case of a patient with HCC who underwent ALPPS and developed liver failure. A living donor liver transplant was performed as a rescue procedure. CASE REPORT: A 49-year-old man with chronic hepatitis B without cirrhosis underwent computed tomography, which revealed an expansive lesion in the right lobe of his liver that was diagnosed as hepatocellular carcinoma. Liver resection was indicated and liver cirrhosis was observed with high portal pressure after transection. The treatment strategy was switched from right hepatectomy to ALPPS. The patient developed severe liver dysfunction and liver transplantation was indicated. His postoperative course was uneventful and 3 months after the procedure the patient was without complications. CONCLUSIONS: Living donor liver transplantation may be necessary as a rescue procedure for patients who underwent ALPPS and develop liver dysfunction.
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spelling pubmed-62385452018-12-10 Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) de Souza Martins Fernandes, Eduardo de Mello, Felipe Pedreira Tavares Andrade, Ronaldo Oliveira Girao, Camila Liberato Pimentel, Leandro Savattone Cesar, Camilla Sousa, Claudia Cristina Brito-Azevedo, Anderson Basto, Samanta Teixeira Torres, Orlando Jorge Martins Am J Case Rep Articles Patient: Male, 49 Final Diagnosis: Hepatocellular carcinoma Symptoms: Abdominal pain Medication: — Clinical Procedure: Liver transplant Specialty: Transplantology OBJECTIVE: Unusual clinical course BACKGROUND: The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) is an important tool to induce fast liver hypertrophy. The degree of hepatic fibrosis/cirrhosis in patients with HCC negatively impacts their health, and the risk of liver failure is always present. In these cases, liver transplantation may be necessary as a rescue procedure. We present the case of a patient with HCC who underwent ALPPS and developed liver failure. A living donor liver transplant was performed as a rescue procedure. CASE REPORT: A 49-year-old man with chronic hepatitis B without cirrhosis underwent computed tomography, which revealed an expansive lesion in the right lobe of his liver that was diagnosed as hepatocellular carcinoma. Liver resection was indicated and liver cirrhosis was observed with high portal pressure after transection. The treatment strategy was switched from right hepatectomy to ALPPS. The patient developed severe liver dysfunction and liver transplantation was indicated. His postoperative course was uneventful and 3 months after the procedure the patient was without complications. CONCLUSIONS: Living donor liver transplantation may be necessary as a rescue procedure for patients who underwent ALPPS and develop liver dysfunction. International Scientific Literature, Inc. 2018-11-09 /pmc/articles/PMC6238545/ /pubmed/30409960 http://dx.doi.org/10.12659/AJCR.911694 Text en © Am J Case Rep, 2018 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
de Souza Martins Fernandes, Eduardo
de Mello, Felipe Pedreira Tavares
Andrade, Ronaldo Oliveira
Girao, Camila Liberato
Pimentel, Leandro Savattone
Cesar, Camilla
Sousa, Claudia Cristina
Brito-Azevedo, Anderson
Basto, Samanta Teixeira
Torres, Orlando Jorge Martins
Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title_full Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title_fullStr Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title_full_unstemmed Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title_short Living Donor Liver Transplant as Rescue Surgery for a Patient with Hepatocellular Carcinoma Who Underwent Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS)
title_sort living donor liver transplant as rescue surgery for a patient with hepatocellular carcinoma who underwent associating liver partition and portal vein ligation for staged hepatectomy (alpps)
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238545/
https://www.ncbi.nlm.nih.gov/pubmed/30409960
http://dx.doi.org/10.12659/AJCR.911694
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