Cargando…
Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabol...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238560/ https://www.ncbi.nlm.nih.gov/pubmed/30532364 http://dx.doi.org/10.4103/aian.AIAN_411_17 |
_version_ | 1783371407396175872 |
---|---|
author | Renjen, Pushpendra Nath Chaudhari, Dinesh Mohan Shilpi, U S Zutshi, Dhruv Ahmad, Kamal |
author_facet | Renjen, Pushpendra Nath Chaudhari, Dinesh Mohan Shilpi, U S Zutshi, Dhruv Ahmad, Kamal |
author_sort | Renjen, Pushpendra Nath |
collection | PubMed |
description | Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabolic and nutritional deficits, or side effects of treatment. When tumor- and treatment-related causes have been excluded, the patient is considered to suffer from paraneoplastic cerebellar degeneration (PCD). We report a case of PCD that presented before any evidence of tumor, but early diagnostic workup and clinical vigilance helped us to find the underlying high-grade ovarian adenocarcinoma which was surgically removed later. |
format | Online Article Text |
id | pubmed-6238560 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-62385602018-12-07 Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature Renjen, Pushpendra Nath Chaudhari, Dinesh Mohan Shilpi, U S Zutshi, Dhruv Ahmad, Kamal Ann Indian Acad Neurol Case Report Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabolic and nutritional deficits, or side effects of treatment. When tumor- and treatment-related causes have been excluded, the patient is considered to suffer from paraneoplastic cerebellar degeneration (PCD). We report a case of PCD that presented before any evidence of tumor, but early diagnostic workup and clinical vigilance helped us to find the underlying high-grade ovarian adenocarcinoma which was surgically removed later. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6238560/ /pubmed/30532364 http://dx.doi.org/10.4103/aian.AIAN_411_17 Text en Copyright: © 2018 Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Renjen, Pushpendra Nath Chaudhari, Dinesh Mohan Shilpi, U S Zutshi, Dhruv Ahmad, Kamal Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title | Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title_full | Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title_fullStr | Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title_full_unstemmed | Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title_short | Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature |
title_sort | paraneoplastic cerebellar degeneration associated with ovarian adenocarcinoma: a case report and review of literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238560/ https://www.ncbi.nlm.nih.gov/pubmed/30532364 http://dx.doi.org/10.4103/aian.AIAN_411_17 |
work_keys_str_mv | AT renjenpushpendranath paraneoplasticcerebellardegenerationassociatedwithovarianadenocarcinomaacasereportandreviewofliterature AT chaudharidineshmohan paraneoplasticcerebellardegenerationassociatedwithovarianadenocarcinomaacasereportandreviewofliterature AT shilpius paraneoplasticcerebellardegenerationassociatedwithovarianadenocarcinomaacasereportandreviewofliterature AT zutshidhruv paraneoplasticcerebellardegenerationassociatedwithovarianadenocarcinomaacasereportandreviewofliterature AT ahmadkamal paraneoplasticcerebellardegenerationassociatedwithovarianadenocarcinomaacasereportandreviewofliterature |