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Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature

Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabol...

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Autores principales: Renjen, Pushpendra Nath, Chaudhari, Dinesh Mohan, Shilpi, U S, Zutshi, Dhruv, Ahmad, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238560/
https://www.ncbi.nlm.nih.gov/pubmed/30532364
http://dx.doi.org/10.4103/aian.AIAN_411_17
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author Renjen, Pushpendra Nath
Chaudhari, Dinesh Mohan
Shilpi, U S
Zutshi, Dhruv
Ahmad, Kamal
author_facet Renjen, Pushpendra Nath
Chaudhari, Dinesh Mohan
Shilpi, U S
Zutshi, Dhruv
Ahmad, Kamal
author_sort Renjen, Pushpendra Nath
collection PubMed
description Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabolic and nutritional deficits, or side effects of treatment. When tumor- and treatment-related causes have been excluded, the patient is considered to suffer from paraneoplastic cerebellar degeneration (PCD). We report a case of PCD that presented before any evidence of tumor, but early diagnostic workup and clinical vigilance helped us to find the underlying high-grade ovarian adenocarcinoma which was surgically removed later.
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spelling pubmed-62385602018-12-07 Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature Renjen, Pushpendra Nath Chaudhari, Dinesh Mohan Shilpi, U S Zutshi, Dhruv Ahmad, Kamal Ann Indian Acad Neurol Case Report Paraneoplastic syndromes are a rare heterogeneous group of disorders that are indicators of the underlying occult malignancy. Subacute cerebellar ataxia in a patient with a known cancer is often due to metastatic invasion or other complications of the cancer, such as infection, coagulopathy, metabolic and nutritional deficits, or side effects of treatment. When tumor- and treatment-related causes have been excluded, the patient is considered to suffer from paraneoplastic cerebellar degeneration (PCD). We report a case of PCD that presented before any evidence of tumor, but early diagnostic workup and clinical vigilance helped us to find the underlying high-grade ovarian adenocarcinoma which was surgically removed later. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6238560/ /pubmed/30532364 http://dx.doi.org/10.4103/aian.AIAN_411_17 Text en Copyright: © 2018 Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Renjen, Pushpendra Nath
Chaudhari, Dinesh Mohan
Shilpi, U S
Zutshi, Dhruv
Ahmad, Kamal
Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title_full Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title_fullStr Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title_full_unstemmed Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title_short Paraneoplastic Cerebellar Degeneration Associated With Ovarian Adenocarcinoma: A Case Report and Review of Literature
title_sort paraneoplastic cerebellar degeneration associated with ovarian adenocarcinoma: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238560/
https://www.ncbi.nlm.nih.gov/pubmed/30532364
http://dx.doi.org/10.4103/aian.AIAN_411_17
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