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Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India
BACKGROUND: Neurocysticercosis (NCC) produces a progressive organic brain damage by altering brain function with alterations in memory, difficulties in learning, and behavioral changes. The present study was designed to compare the cognitive and behavioral profile of school-going children aged 6–14...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238579/ https://www.ncbi.nlm.nih.gov/pubmed/30532361 http://dx.doi.org/10.4103/aian.AIAN_22_18 |
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author | Verma, Anjali Chopra, Bhavna Kaushik, Jaya Shankar Gathwala, Geeta |
author_facet | Verma, Anjali Chopra, Bhavna Kaushik, Jaya Shankar Gathwala, Geeta |
author_sort | Verma, Anjali |
collection | PubMed |
description | BACKGROUND: Neurocysticercosis (NCC) produces a progressive organic brain damage by altering brain function with alterations in memory, difficulties in learning, and behavioral changes. The present study was designed to compare the cognitive and behavioral profile of school-going children aged 6–14 years with newly diagnosed NCC with their age-matched controls. MATERIALS AND METHODS: A descriptive cross-sectional study was conducted among children aged 6–14 years with newly (<7 days) diagnosed NCC. Age- and gender-matched typically developing children with minor illness attending outpatient facility served as control. Intelligence and behavioral assessment were performed using Malin's Intelligence Scale for Indian Children and Childhood Behavior Checklist (CBCL) (school age version CBCL/6–18). CBCL T-scores were computed and scores < 60 were considered as normal, 60–63 as borderline, and > 63 as clinical range. RESULTS: A total of 35 cases and 35 controls were enrolled. Baseline demographic characteristics were comparable between the two groups. Verbal intelligence quotient (IQ) scores were comparable between the cases (96.14 [10.23]) and controls (100.17 [10.89]) (P = 0.11). The behavioral assessment revealed normal T-scores (<60) in both the groups. CONCLUSIONS: The study revealed comparable IQ and normal behavioral profile of treatment-naïve children with recently diagnosed NCC to their age-matched peers. Further studies with larger sample size and longitudinal study design are required to evaluate the role of NCC on cognition and behavior in Indian children. |
format | Online Article Text |
id | pubmed-6238579 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-62385792018-12-07 Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India Verma, Anjali Chopra, Bhavna Kaushik, Jaya Shankar Gathwala, Geeta Ann Indian Acad Neurol Short Communication BACKGROUND: Neurocysticercosis (NCC) produces a progressive organic brain damage by altering brain function with alterations in memory, difficulties in learning, and behavioral changes. The present study was designed to compare the cognitive and behavioral profile of school-going children aged 6–14 years with newly diagnosed NCC with their age-matched controls. MATERIALS AND METHODS: A descriptive cross-sectional study was conducted among children aged 6–14 years with newly (<7 days) diagnosed NCC. Age- and gender-matched typically developing children with minor illness attending outpatient facility served as control. Intelligence and behavioral assessment were performed using Malin's Intelligence Scale for Indian Children and Childhood Behavior Checklist (CBCL) (school age version CBCL/6–18). CBCL T-scores were computed and scores < 60 were considered as normal, 60–63 as borderline, and > 63 as clinical range. RESULTS: A total of 35 cases and 35 controls were enrolled. Baseline demographic characteristics were comparable between the two groups. Verbal intelligence quotient (IQ) scores were comparable between the cases (96.14 [10.23]) and controls (100.17 [10.89]) (P = 0.11). The behavioral assessment revealed normal T-scores (<60) in both the groups. CONCLUSIONS: The study revealed comparable IQ and normal behavioral profile of treatment-naïve children with recently diagnosed NCC to their age-matched peers. Further studies with larger sample size and longitudinal study design are required to evaluate the role of NCC on cognition and behavior in Indian children. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC6238579/ /pubmed/30532361 http://dx.doi.org/10.4103/aian.AIAN_22_18 Text en Copyright: © 2018 Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Short Communication Verma, Anjali Chopra, Bhavna Kaushik, Jaya Shankar Gathwala, Geeta Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title | Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title_full | Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title_fullStr | Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title_full_unstemmed | Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title_short | Cognitive and Behavioral Profile of Treatment-Naïve Children Aged 6–14 Years with Neurocysticercosis from North India |
title_sort | cognitive and behavioral profile of treatment-naïve children aged 6–14 years with neurocysticercosis from north india |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238579/ https://www.ncbi.nlm.nih.gov/pubmed/30532361 http://dx.doi.org/10.4103/aian.AIAN_22_18 |
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