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Phosphorylation of Arp2 is not essential for Arp2/3 complex activity in fission yeast

LeClaire et al presented evidence that phosphorylation of three sites on the Arp2 subunit activates the Arp2/3 complex to nucleate actin filaments. We mutated the homologous residues of Arp2 (Y198, T233, and T234) in the fission yeast genome to amino acids that preclude or mimic phosphorylation. Arp...

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Detalles Bibliográficos
Autores principales: Epstein, Alexander E, Espinoza-Sanchez, Sofia, Pollard, Thomas D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238581/
https://www.ncbi.nlm.nih.gov/pubmed/30456391
http://dx.doi.org/10.26508/lsa.201800202

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