Co-existing feedback loops generate tissue-specific circadian rhythms

Gene regulatory feedback loops generate autonomous circadian rhythms in mammalian tissues. The well-studied core clock network contains many negative and positive regulations. Multiple feedback loops have been discussed as primary rhythm generators but the design principles of the core clock and dif...

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Detalles Bibliográficos
Autores principales: Pett, J Patrick, Kondoff, Matthew, Bordyugov, Grigory, Kramer, Achim, Herzel, Hanspeter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238625/
https://www.ncbi.nlm.nih.gov/pubmed/30456356
http://dx.doi.org/10.26508/lsa.201800078

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