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Nucleolar Localization of HIV-1 Rev Is Required, Yet Insufficient for Production of Infectious Viral Particles

Combination antiretroviral therapy fails in complete suppression of HIV-1 due to drug resistance and persistent latency. Novel therapeutic intervention requires knowledge of intracellular pathways responsible for viral replication, specifically those untargeted by antiretroviral drugs. An understudi...

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Detalles Bibliográficos
Autores principales: Arizala, Jerlisa Ann C., Takahashi, Mayumi, Burnett, John C., Ouellet, Dominique L., Li, Haitang, Rossi, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238656/
https://www.ncbi.nlm.nih.gov/pubmed/29804468
http://dx.doi.org/10.1089/aid.2017.0306