Cargando…

Repurposing existing drugs for cardiovascular risk management: a focus on methotrexate

About 20% of patients with a history of atherosclerotic cardiovascular disease will experience further cardiovascular events despite maximal pharmacological treatment with cardioprotective drugs. This highlights the presence of residual cardiovascular risk in a significant proportion of patients and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mangoni, Arduino A, Tommasi, Sara, Zinellu, Angelo, Sotgia, Salvatore, Carru, Ciriaco, Piga, Matteo, Erre, Gian Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioExcel Publishing Ltd 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239018/ https://www.ncbi.nlm.nih.gov/pubmed/30459819 http://dx.doi.org/10.7573/dic.212557

Ejemplares similares

Protective Effects of Methotrexate against Proatherosclerotic Cytokines: A Review of the Evidence
por: Mangoni, Arduino A., et al.
Publicado: (2017)

A Capillary Electrophoresis-Based Method for the Measurement of Hydroxychloroquine and Its Active Metabolite Desethyl Hydroxychloroquine in Whole Blood in Patients with Rheumatoid Arthritis
por: Sotgia, Salvatore, et al.
Publicado: (2022)

B-Type Natriuretic Peptide Concentrations, COVID-19 Severity, and Mortality: A Systematic Review and Meta-Analysis With Meta-Regression
por: Zinellu, Angelo, et al.
Publicado: (2021)

Oxidative Stress Biomarkers and Peripheral Endothelial Dysfunction in Rheumatoid Arthritis: A Monocentric Cross-Sectional Case-Control Study
por: Bassu, Stefania, et al.
Publicado: (2020)

Strategies to enhance graphic and results interpretation of a regression-based approach for method comparison studies
por: Sotgia, Salvatore, et al.
Publicado: (2017)

Meta-Analysis of Asymmetric Dimethylarginine Concentrations in Rheumatic Diseases
por: Erre, Gian Luca, et al.
Publicado: (2019)

Association between Paraoxonase/Arylesterase Activity of Serum PON-1 Enzyme and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
por: Erre, Gian Luca, et al.
Publicado: (2022)

Methodological Fallacies in the Determination of Serum/Plasma Glutathione Limit Its Translational Potential in Chronic Obstructive Pulmonary Disease
por: Sotgia, Salvatore, et al.
Publicado: (2021)

Hercynine, Ergothioneine and Redox State in Stallion’s Seminal Plasma
por: Sotgia, Salvatore, et al.
Publicado: (2020)

Does hyperglycemia affect arginine metabolites in critically ill patients? A prospective cohort and in vitro study
por: Lee, Tien F., et al.
Publicado: (2023)

Evaluation of oxidative stress biomarkers in idiopathic pulmonary fibrosis and therapeutic applications: a systematic review
por: Fois, Alessandro G., et al.
Publicado: (2018)

Clinical and Biochemical Correlates of Serum L-Ergothioneine Concentrations in Community-Dwelling Middle-Aged and Older Adults
por: Sotgia, Salvatore, et al.
Publicado: (2014)

Plasma L-Ergothioneine Measurement by High-Performance Liquid Chromatography and Capillary Electrophoresis after a Pre-Column Derivatization with 5-Iodoacetamidofluorescein (5-IAF) and Fluorescence Detection
por: Sotgia, Salvatore, et al.
Publicado: (2013)

Diagnostic accuracy of different blood cells-derived indexes in rheumatoid arthritis: A cross-sectional study
por: Erre, Gian Luca, et al.
Publicado: (2020)

Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
por: Zinellu, Angelo, et al.
Publicado: (2017)

Arginines Plasma Concentration and Oxidative Stress in Mild to Moderate COPD
por: Zinellu, Angelo, et al.
Publicado: (2016)

Neutrophil to lymphocyte ratio and clinical outcomes in COPD: recent evidence and future perspectives
por: Paliogiannis, Panagiotis, et al.
Publicado: (2018)

Serum amyloid A concentrations, COVID-19 severity and mortality: An updated systematic review and meta-analysis
por: Zinellu, Angelo, et al.
Publicado: (2021)

Serum hydroxybutyrate dehydrogenase and COVID-19 severity and mortality: a systematic review and meta-analysis with meta-regression
por: Zinellu, Angelo, et al.
Publicado: (2021)

INR and COVID-19 severity and mortality: A systematic review with meta-analysis and meta-regression
por: Zinellu, Angelo, et al.
Publicado: (2021)

Development of an LC–Tandem Mass Spectrometry Method for the Quantitative Analysis of Hercynine in Human Whole Blood
por: Sotgia, Salvatore, et al.
Publicado: (2018)

Serum thiols and cardiovascular risk scores: a combined assessment of transsulfuration pathway components and substrate/product ratios
por: Mangoni, Arduino A, et al.
Publicado: (2013)

Systematic Review and Meta-Analysis of the Blood Glutathione Redox State in Chronic Obstructive Pulmonary Disease
por: Sotgia, Salvatore, et al.
Publicado: (2020)

Identification of the Main Intermediate Precursor of l-Ergothioneine Biosynthesis in Human Biological Specimens
por: Sotgia, Salvatore, et al.
Publicado: (2016)

Effects of Ramipril and Telmisartan on Plasma Concentrations of Low Molecular Weight and Protein Thiols and Carotid Intima Media Thickness in Patients with Chronic Kidney Disease
por: Zinellu, Angelo, et al.
Publicado: (2016)

Effect of statin treatment on circulating malondialdehyde concentrations: a systematic review and meta-analysis
por: Zinellu, Angelo, et al.
Publicado: (2019)

A Systematic Review of the Prognostic Significance of the Body Mass Index in Idiopathic Pulmonary Fibrosis
por: Zinellu, Angelo, et al.
Publicado: (2023)

Transsulfuration Pathway Thiols and Methylated Arginines: The Hunter Community Study
por: Mangoni, Arduino A., et al.
Publicado: (2013)

Paraoxonase and arylesterase activity of serum PON-1 enzyme in psoriatic patients: a systematic review and meta-analysis
por: Bassu, Stefania, et al.
Publicado: (2022)

Red blood cell distribution width in pregnancy: a systematic review
por: Paliogiannis, Panagiotis, et al.
Publicado: (2018)

Cholesterol and Triglyceride Concentrations, COVID-19 Severity, and Mortality: A Systematic Review and Meta-Analysis With Meta-Regression
por: Zinellu, Angelo, et al.
Publicado: (2021)

Serum albumin concentrations are associated with disease severity and outcomes in coronavirus 19 disease (COVID-19): a systematic review and meta-analysis
por: Paliogiannis, Panagiotis, et al.
Publicado: (2021)

A Comprehensive Systematic Review and Meta-Analysis of the Association between the Neutrophil-to-Lymphocyte Ratio and Adverse Outcomes in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
por: Zinellu, Angelo, et al.
Publicado: (2022)

Clinical significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in acute exacerbations of COPD: present and future
por: Zinellu, Angelo, et al.
Publicado: (2022)

Serum CK-MB, COVID-19 severity and mortality: An updated systematic review and meta-analysis with meta-regression
por: Zinellu, Angelo, et al.
Publicado: (2021)

Protective Effects of Hydroxychloroquine against Accelerated Atherosclerosis in Systemic Lupus Erythematosus
por: Floris, Alberto, et al.
Publicado: (2018)

Serum Albumin Concentrations in Stable Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis
por: Zinellu, Elisabetta, et al.
Publicado: (2021)

Circulating Superoxide Dismutase Concentrations in Obstructive Sleep Apnoea (OSA): A Systematic Review and Meta-Analysis
por: Pau, Maria Carmina, et al.
Publicado: (2021)

Paraoxonase-1 Concentrations in Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis
por: Pau, Maria Carmina, et al.
Publicado: (2022)

Current smoking predicts inadequate response to methotrexate monotherapy in rheumatoid arthritis patients naïve to DMARDs: Results from a retrospective cohort study
por: Floris, Alberto, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7gghkggvk84qohi4tl7tq6pd7u