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Association of MLH1 single nucleotide polymorphisms with clinical outcomes of first-line irinotecan-based chemotherapy in colorectal cancer

PURPOSE: Several studies have proved that single nucleotide polymorphisms (SNPs) of mismatch repair system genes are closely related to the development of colorectal cancer (CRC) by causing microsatellite instability, while effects of the SNPs of MMR system-related genes on the clinical outcomes of...

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Detalles Bibliográficos
Autores principales:	Wang, Deqiang, Zhang, Xiaomei, Zhang, Yan, Wu, Yuan, Guan, Xin, Zhu, Wei, Wang, Mei, Qi, Chuang, Shen, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239120/ https://www.ncbi.nlm.nih.gov/pubmed/30519050 http://dx.doi.org/10.2147/OTT.S180145

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