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Renal miR-148b is associated with megalin down-regulation in IgA nephropathy

Megalin is essential for proximal tubule reabsorption of filtered proteins, hormones, and vitamins, and its dysfunction has been reported in IgA nephropathy (IgAN). miR-148b has been shown to regulate renal megalin expression in vitro and in animal models of kidney disease. We examined a potential r...

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Detalles Bibliográficos
Autores principales: Wen, Lu, Zhao, Zhanzheng, Xiao, Jing, Wang, Zheng, He, Xiangfei, Birn, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239259/
https://www.ncbi.nlm.nih.gov/pubmed/30355654
http://dx.doi.org/10.1042/BSR20181578

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