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Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats
Myostatin gene (MSTN) can inhibit the proliferation of myoblast, which in turn promotes muscle growth and inhibits adipocyte differentiation in livestock. MSTN mutation may lead to muscle hypertrophy or double-muscled (DM) phenotype. MSTN mutation animal, such as sheep, dog, and rabbit have been gen...
Autores principales: | He, Zhengyi, Zhang, Ting, Jiang, Lei, Zhou, Minya, Wu, Daijin, Mei, Junyan, Cheng, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239268/ https://www.ncbi.nlm.nih.gov/pubmed/30201688 http://dx.doi.org/10.1042/BSR20180742 |
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