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Use of CRISPR/Cas9 technology efficiently targetted goat myostatin through zygotes microinjection resulting in double-muscled phenotype in goats

Myostatin gene (MSTN) can inhibit the proliferation of myoblast, which in turn promotes muscle growth and inhibits adipocyte differentiation in livestock. MSTN mutation may lead to muscle hypertrophy or double-muscled (DM) phenotype. MSTN mutation animal, such as sheep, dog, and rabbit have been gen...

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Detalles Bibliográficos
Autores principales:	He, Zhengyi, Zhang, Ting, Jiang, Lei, Zhou, Minya, Wu, Daijin, Mei, Junyan, Cheng, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239268/ https://www.ncbi.nlm.nih.gov/pubmed/30201688 http://dx.doi.org/10.1042/BSR20180742

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