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MiR-199a-3p inhibits proliferation and induces apoptosis in rheumatoid arthritis fibroblast-like synoviocytes via suppressing retinoblastoma 1

Background Fibroblast-like synoviocytes (FLSs) that line the intimal synovium play a crucial role in the pathogenesis of rheumatoid arthritis (RA). miR-199a-3p is a highly conserved miRNA that has been shown to regulate a variety of growth behaviors in diverse cell types. However, the role of miR-19...

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Detalles Bibliográficos
Autores principales: Wangyang, Yufan, Yi, Linhong, Wang, Tao, Feng, Yanbo, Liu, Guangwang, Li, Dongya, Zheng, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239273/
https://www.ncbi.nlm.nih.gov/pubmed/30352835
http://dx.doi.org/10.1042/BSR20180982