Ribosome display for the rapid generation of high-affinity Zika-neutralizing single-chain antibodies

BACKGROUND: Zika virus (ZIKV) is an emerging pathogen with no approved therapeutics and only limited diagnostics available. To address this gap, six mouse single-chain antibodies (scFvs) to ZIKV envelope (E) protein were isolated rapidly and efficiently from a ribosome-displayed antibody library con...

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Detalles Bibliográficos
Autores principales: Kunamneni, Adinarayana, Ye, Chunyan, Bradfute, Steven B., Durvasula, Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239285/
https://www.ncbi.nlm.nih.gov/pubmed/30444865
http://dx.doi.org/10.1371/journal.pone.0205743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239285/
https://www.ncbi.nlm.nih.gov/pubmed/30444865
http://dx.doi.org/10.1371/journal.pone.0205743

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