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Ribosome display for the rapid generation of high-affinity Zika-neutralizing single-chain antibodies
BACKGROUND: Zika virus (ZIKV) is an emerging pathogen with no approved therapeutics and only limited diagnostics available. To address this gap, six mouse single-chain antibodies (scFvs) to ZIKV envelope (E) protein were isolated rapidly and efficiently from a ribosome-displayed antibody library con...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239285/ https://www.ncbi.nlm.nih.gov/pubmed/30444865 http://dx.doi.org/10.1371/journal.pone.0205743 |