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A computational analysis of dynamic, multi-organ inflammatory crosstalk induced by endotoxin in mice

Bacterial lipopolysaccharide (LPS) induces an acute inflammatory response across multiple organs, primarily via Toll-like receptor 4 (TLR4). We sought to define novel aspects of the complex spatiotemporal dynamics of LPS-induced inflammation using computational modeling, with a special focus on the...

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Detalles Bibliográficos
Autores principales:	Zamora, Ruben, Korff, Sebastian, Mi, Qi, Barclay, Derek, Schimunek, Lukas, Zucca, Riccardo, Arsiwalla, Xerxes D., Simmons, Richard L., Verschure, Paul, Billiar, Timothy R., Vodovotz, Yoram
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239343/ https://www.ncbi.nlm.nih.gov/pubmed/30399158 http://dx.doi.org/10.1371/journal.pcbi.1006582

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