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Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy

One of the key pathological features of Alzheimer’s disease (AD) is the existence of extracellular deposition of amyloid plaques formed with misfolded amyloid-β (Aβ). The conformational change of proteins leads to enriched contents of β sheets, resulting in remarkable changes of vibrational spectra,...

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Detalles Bibliográficos
Autores principales:	Ji, Minbiao, Arbel, Michal, Zhang, Lili, Freudiger, Christian W., Hou, Steven S., Lin, Dongdong, Yang, Xinju, Bacskai, Brian J., Xie, X. Sunney
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239428/ https://www.ncbi.nlm.nih.gov/pubmed/30456301 http://dx.doi.org/10.1126/sciadv.aat7715

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