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Evidence of Polygenic Adaptation to High Altitude from Tibetan and Sherpa Genomes

Although Tibetans and Sherpa present several physiological adjustments evolved to cope with selective pressures imposed by the high-altitude environment, especially hypobaric hypoxia, few selective sweeps at a limited number of hypoxia related genes were confirmed by multiple genomic studies. Nevert...

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Detalles Bibliográficos
Autores principales: Gnecchi-Ruscone, Guido A, Abondio, Paolo, De Fanti, Sara, Sarno, Stefania, Sherpa, Mingma G, Sherpa, Phurba T, Marinelli, Giorgio, Natali, Luca, Di Marcello, Marco, Peluzzi, Davide, Luiselli, Donata, Pettener, Davide, Sazzini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239493/
https://www.ncbi.nlm.nih.gov/pubmed/30335146
http://dx.doi.org/10.1093/gbe/evy233