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Evidence of Polygenic Adaptation to High Altitude from Tibetan and Sherpa Genomes
Although Tibetans and Sherpa present several physiological adjustments evolved to cope with selective pressures imposed by the high-altitude environment, especially hypobaric hypoxia, few selective sweeps at a limited number of hypoxia related genes were confirmed by multiple genomic studies. Nevert...
Autores principales: | Gnecchi-Ruscone, Guido A, Abondio, Paolo, De Fanti, Sara, Sarno, Stefania, Sherpa, Mingma G, Sherpa, Phurba T, Marinelli, Giorgio, Natali, Luca, Di Marcello, Marco, Peluzzi, Davide, Luiselli, Donata, Pettener, Davide, Sazzini, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239493/ https://www.ncbi.nlm.nih.gov/pubmed/30335146 http://dx.doi.org/10.1093/gbe/evy233 |
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